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RELATIONSHIP BETWEEN VASCULAR, LYMPHATIC INFILTRATION AND AXILLARY LYMPH NODE STATUS OF INVASIVE BREAST CANCER
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Abstract
Evaluation of axillary lymph node metastasis in breast cancer is extremely important in the treatment and prognosis. Additionally, vascular and lymphatic infiltration is an important criterion for the prediction of early recurrence and distal metastasis, especially in patients without lymph node metastasis. Purpose: Assessment of the relationship between vascular, lymphatic infiltration and axillary lymph nodes status of invasive breast cancer. Methods: 300 breast cancer patients were assessed for vascular and lymphatic invation through IHC staining with CD31, D2-40 and evaluated for association with axillary lymph node condition. Results: In breast cancer group of 3 metastatic lymph nodes and the positive blood vessel infiltration, percentage was the highest (54.7%). Similarly, the group of 3 lymph node metastasis and present lymphatic infiltration also accounted for the highest percentage (47.3%). On the contrast, 70.9% of cases were not lymph node metastasis and vascular infiltration and 73.9% were not lymph node metastasis and lymphatic invation (p<0.001). Conclusion: Vascular and or lymphatic infiltration is strongly associated with axillary lymph node status.
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Keywords
Breast cancer, Vessel invasion, Node status
References
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