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RESEARCH OF FACTORS RELATED TO MORTALITY IN PATIENTS WITH METHANOL POISONING
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Abstract
Objective: to evaluate the factors related to fatal outcome in the patients with acute methanol poisoning. Subjects and Methods: A analysis observational study included 107 patients with methanol intoxication treated at Poison Control Center of Bach Mai Hospital from January 2016 to July 2019. Results: The study patients were mainly male (97.2%), the mean age were 47.6 ± 12.6 years and mainly in the age group of 40-59 (65.4%). Methanol poisoning is severe with high mortality rate (41.1%). Some main factors related to death in patients with acute methanol poisoning: delay admission (more than 24 hours from ingestion to hoospital admission) (OR 1.04; p <0.05); deep coma on admission (OR 0.24; p <0.05); severe metabolic acidosis pH <7.0 (OR 0.22; p<0.05; acute renal failure (OR 5.13; p <0.05); hyperglycemia (OR 13.28; p <0,05); Hypotension requires vasopressors (OR 0.019; p <0.01). Conlusion: The study showed the association between some clinical, laboratory and therapeutic predictors with mortality in patients with acute methanol poisoning.
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Keywords
methanol poisoning, mortality, predictors
References
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