ASSESSMENT OF HYPOALBUMINEMIA IN PNEUMONITIS IN CHILDREN FROM 2 MONTHS TO UNDER 5 YEARS OLD AT CA MAU OBSTETRICS AND GYNECOLOGY HOSPITAL 2022-2023

Thị Như Ý Trần1,, Quốc Trung Lý2, Hồng Ngân Nguyễn3, Thị Thảo Mai Hà3, Đỗ Hùng Trần3
1 Ca Mau Obstetrics and Children's Hospital
2 STCC
3 Can Tho University of Medicine - Pharmacy

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Abstract

Background: Pneumonia is a leading cause of mortality in children worldwide. To further understand the impact of reduced serum albumin on the condition of children with pneumonia, we have proceeded this research. Objectives: (1) To determine the rate of hypoalbuminemia in hospitalized children with pneumonia at Ca Mau Obstetrics and Pediatrics Hospital. (2) To assess the association between hypoalbuminemia and pneumonia in children from 2 months to under 5 years old at Ca Mau Obstetrics and Pediatrics Hospital. Materials and methods: A cross-sectional descriptive study was conducted on 202 children aged 2 months to under 5 years who were diagnosed with pneumonia and admitted to Ca Mau Obstetrics and Pediatrics Hospital from 11/2022 to 04/2023. Results: The rate male patients accounted for 55.9% and female patients accounted for 44.1%. The mean age of patients was 21,75 ± 15,59 months-old. The most patients in the group from 2 months to 2 years-old accounted for 59.9%. The average serum albumin levels in the study subjects was 38,43±2,27g/L. The rate of pneumonia patients with low serum albumin levels and those without low serum albumin was 22.8% and 77.2% respectively. The percentage of male patients with low serum albumin levels was 16.8%, higher than female patients with 5.9%, the differences were statistically significant, p<0,05. The proportion of patients with hypoalbuminemia in group from 2 months to 2 years-old accounted for 14.9% higher than the group from 2 to under 5 years-old with a rate of 7.9%, but the differences were not statistically significant, p>0,05. The proportion of patients with hypoalbuminemia in pneumonia level was 20,3%, higher than the 3% in the group severe pneumonia (p>0.05). Similarly, the proportion of patients with hypoalbuminemia in pneumonia who received ≥2 types of antibiotics was 2.5%, in the group who received 1 type of antibiotic was 4%, (p<0.05). Conclusion: Hypoalbuminemia in pediatric pneumonia was related to sex, the proportion of boy patients was higher than that of girls. Hypoalbuminemia in pediatric pneumonia was not a factor associated with the severity or increase in the number of antibiotics used in pneumonia

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References

1. Nguyễn Đình Chung (2019), Tình trạng dinh dưỡng và thiếu máu thiếu sắt ở trẻ viêm phổi từ 1-24 tháng tuổi tại Bệnh viện Nhi Trung Ương, Luận án Chuyên khoa II, Trường Đại học Y Hà Nội.
2. Nguyễn Thị Hà và cộng sự (2020), "Đặc điểm lâm sàng và căn nguyên vi khuẩn gây viêm phổi cộng đồng trẻ em tại khoa Quốc tế Bệnh viện Nhi Trung Ương", Tạp chí nghiên cứu Y học, 131(7), tr.67-73.
3. Nguyễn Thị Hồng Nhân, Nguyễn Văn Long (2019), "Mối liên quan giữa thiếu máu thiếu sắt và tình trạng mắc bệnh viêm phổi ở trẻ em dưới 5 tuổi được khám và điều trị tại Bệnh viện Đa khoa Xanh Pôn năm 2017", Tạp chí Nghiên cứu và thực hành Nhi khoa, 2, tr.37-47.
4. Nguyễn Đức Trí (2019), Nghiên cứu tình hình thiếu vitamin D ở trẻ viêm phổi từ 2 tháng đến 5 tuổi tại Bệnh viện Nhi đồng thành phố Cần Thơ, Trường Đại học Y dược Cần Thơ.
5. Meganathan P, Awasthi S (2019), "Predicting Complicated Parapneumonic Effusion in Community Acquired Pneumonia: Hospital Based Case-Control Study", Indian J Pediatr, 86(2), pp.140-147.
6. Lumin Chen et al (2021), "Age-specific risk factors of severe pneumonia among pediatric patients hospitalized with community-acquired pneumonia", Ital J Pediatr, pp.47-100.
7. V Gounden et al (2022), Hypoalbuminemia, StatPearls Internet, Treasure Island (FL).
8. Jae Hyuk Lee, J. Kim, et al (2011), "Albumin and C-reactive protein have prognostic significance in patients with community-acquired pneumonia", Journal of Critical Care, 26(3), pp.287-294.
9. Hiroyuki Miyazaki (2018), "Comprehensive analysis of prognostic factors in hospitalized patients with pneumonia occurring outside hospital: serum albumin is not less important than pneumonia severity assessment scale", J Journal of infection chemotherapy, 24(8), pp.602-609.
10. Otal Y et al (2022), "A new biomarker in severe pneumonia associated with coronavirus disease 2019: hypoalbuminemia. A prospective study", Sao Paulo Med J, 140(3), pp.378-383.