ĐÁNH GIÁ HIỆU QUẢ CỦA PHÁC ĐỒ ĐIỀU TRỊ CƠN PHẢN ỨNG PHONG THEO TỔ CHỨC Y TẾ THẾ GIỚI TẠI THÀNH PHỐ HỒ CHÍ MINH

Abstract

Background: Leprosy reactions is one of the main causes of impaired motor function, sensory disturbances, and autonomic nervous system disorders. Objectives: assess the effectiveness of the WHO standard treatment protocol for reactional leprosy in Ho Chi Minh City over the period from 30/06/2006 to 30/06/2016. Materials and Methods: A series of cases were studied among patients with leprosy reactions managed in Ho Chi Minh City. Results: Treatment response evaluation based on the sensory test showed that 38.3% of patients did not respond to treatment, 10.5% had a complete response, and 48.8% were classified as normal. Evaluation of treatment response based on disability grading revealed that 32.6% of patients did not respond to treatment, 8.1% had an incomplete response, 10.5% had a complete response, and 48.8% were considered normal. Only the average number of treatment weeks showed a statistically significant difference in response evaluation based on disability grading. Conclusions: The proportion of patients who did not respond to treatment according to the WHO standard protocol was relatively high. Further expanded research with a larger number of patients is needed to clarify the findings of this study.