TO ASSESS THE IN VITRO TOXICITY OF SILICONE INTERVERTEBRAL JOINTS MANUFACTURED BY THE BIOMEDICAL MATERIALS RESEARCH AND DEVELOPMENT INSTITUTE

Thị Hồng Nhung Lê1,, Thị Thùy Dương Lê2, Văn Hoàng Nguyễn3
1 HMU
2 Institute of Biotechnology
3 Biomedical Materials Research and Development Institute

Main Article Content

Abstract

Objective: To assess the in vitro toxicity of silicone intervertebral joints manufactured by the Biomedical Materials Research and Development Institute. Subjects and methods: Evaluation of HEK-293 line cytotoxic activity (ATCC® CRL-1573TM) was carried out based on MTT method (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium) on 20 samples of silicone intervertebral joints manufactured by the Biomedical Materials Research and Development Institute. Results and conclusions: After testing with MTT kit, calculating OD values, the results show that the specimens were not cytotoxic to the HEK-293 line

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References

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