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CONCENTRATION STUDY TRIGLYCERID IN HDL AND SOME CORRELATIVE FACTORS IN HYPERTENSIVE PATIENTS WITH TYPE 2 DIABETES AT CAN THO CITY GENERAL HOSPITAL IN 2022-2023
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Abstract
Background: Hypertension and diabetes are chronic uncommunicable diseases around the world, as well as in Vietnam. The cause of these two diseases is metabolic disorder, which is most typical of blood dyslipidemia and is one of the leading mortality risks in cardiovascular disease. In Vietnam, cardiovascular disease was responsible for 31% of all deaths in 2016 - more than 170,000 people. Hypertriglyceridemia is a clinical condition associated with increased cardiovascular risk. Its impact on HDL function. In fact, HDL-T concentration has not been evaluated and is not measured in medical facilities, so we conducted a study on HDL-T concentration in hypertensive patients with type 2 diabetes. This section provides more information about this test indicator. Objective: Determination of HDL-T concentration and some correlation factors in hypertensive patients with type 2 diabetes at Can Tho City General Hospital in 2022-2023. Materials and methods: A case-control study on 168 subjects aged 40 years and older was divided into 4 groups (control groups 1: 42 people without the disease, control group 2: 42 people with hypertension, control group 3: 42 people with type 2 diabetes, group disease: 42 people hypertensive patients with type 2 diabetes). Results: HDL-T concentration in control group 1 was (0.19 ± 0.07mmol/l), control group 2 was (0.31 ± 0.13mmol/l), control group 3 was (0.25 ± 0.11mmol/l), disease group was (0.38 ± 0.17mmol/l). The correlation between HDL-T concentration in the disease group was glucose (r=0.63; p< 0.05), triglycerides (r=0.91; p<0.05), total cholesterol (r=0.21; p>0.05), HDL-C (r=-0.07; p>0.05), LDL-C (r=0.21; p>0.05). Conclusions: The concentration of HDL-T was highest in the disease group (0.38 ± 0.17 mmol/l) compared with the control group, and the difference was statistically significant (p<0.05). HDL-T concentration had a very strong positive correlation with triglycerides concentration and a moderately positive correlation with glucose concentration. HDL-T levels had no correlation with total cholesterol, HDL-C, LDL-C.
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Keywords
Hypertension, diabetes, triglycerides, HDL-T.
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