CLINICAL FEATURES, SUBCLINICAL CHARACTERISTICS AND THE RESULTS OF RESPIRATORY POLYGRAPHY IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME AT RESPIRATORY OUTPATIENT CLINICS OF TAM ANH HOSPITAL

Văn Ngân Nguyễn1,2,, Thị Thơm Phùng2, Quý Châu Ngô2, Thị Hạnh Chu2
1 HMU
2 Tam Anh General Hospital in Hanoi

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Abstract

Background: Obstructive sleep apnea is a chronic respiratory disorder characterized by repeated episodes of apnea and hypopnea due to upper airway obstruction1. Patients with sleep apnea often have high risk for medical conditions such as hypertension, diabetes, fat metabolism disorders and coronary artery disease, heart failure. In Viet Nam, the prevalance of OSA has been increasing in recent years but there are many difficulties in diagnosing due to patients’ lack of serious attention to symptoms, and poor devices. Objective: Describe clinical features, paraclinical characteristics and the results of respiratory polygraphy in patients with obstructive sleep apnea syndrome. Subjects and Methods: A cross-sectional study was carried 57 patients with obstructive sleep apnea syndrome at Tam Anh hospital from march, 2022 to february, 2023. Results: The most common nighttime symptom was loud snoring (93,0%), 33,3% of the patients had excessive daytime sleepiness, 89,5% of the patients had  a body mass index ≥ 23 (kg/m2). Mean neck circumference: 39,85 ± 2,98 cm. There was statistically significant difference of neck circumference between men and women (p < 0,05). 66,7% of patients had Mallampati grade III - IV (n=33). ENT endoscopy (n = 33): Nasal turbinate hypertrophy (30,3%). Spirometry: signs of restrictive ventilatory disorder (17,2%), obstructive ventilatory disorder (10,3%). An average apnea-hypopnea index (AHI) of 35,1 ± 24,16 (n=57). 77,2% of patients have moderate to severe AHI. Average SpO2: 92,56 ± 2,78%. Minimum pulse oximetry SpO2: 47%. Desaturation below 90%: 13,88 ± 18,93%. Conclusion: Loud snoring, excessive daytime sleepiness, overweight, obesity, large neck circumference, grade 3-4 Mallampati are common signs and symptoms in patients with obstructive sleep apnea. Respiratory polygraphy is an useful tool in diagnosis and classification of the severity of OSA.

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References

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