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Date Published: 30/08/2023
Abstract Views: 158
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DOI: https://doi.org/10.51298/vmj.v529i1B.6423
Issue
Vol. 529 No. 1B (2023)
Section
Các bài báo
How to Cite
Trần, B. K. H., & Đào, V. H. (2023). EVALUATION OF LOWER ESOPHAGEAL SPHINCTER PRESSURE AND ESOPHAGEAL MOTILITY IN PATIENTS WITH TYPE 2 DIABETES MELLITUS WITH REFLUX SYMPTOMS OF GASTROESOPHAGEAL REFLUX. Vietnam Medical Journal, 529(1B). https://doi.org/10.51298/vmj.v529i1B.6423

EVALUATION OF LOWER ESOPHAGEAL SPHINCTER PRESSURE AND ESOPHAGEAL MOTILITY IN PATIENTS WITH TYPE 2 DIABETES MELLITUS WITH REFLUX SYMPTOMS OF GASTROESOPHAGEAL REFLUX

Bá Khánh Hoan Trần1,, Việt Hằng Đào2,3
1 Ha Tinh Province General Hospital
2 HMU
3 Gastroenterology - Hepatobiliary Research and Training Institute

Main Article Content

Abstract

Objectives: The study investigates the lower esophageal sphincter characteristics and esophageal motility performed by high-resolution manometry (HRM) in type 2 diabetes mellitus patients with gastroesophageal reflux symptoms. Subjects: 62 patients with reflux symptoms (including 31 type 2 diabetes patients and 31 patients without diabetes). Results: The median of the upper esophageal sphincter (UES) pressure, resting pressure of lower esophageal sphincter (LES), and 4-s integrated relaxation pressure (IRP4s) in the diabetes patients’ group were lower significantly than patients without diabetes (p<0,05). The percentage of esophageal motility disorder in diabetes patients was significantly higher than in the group of patients without diabetes; with 71,0% and 41,9% respectively (p < 0,05). In type 2 diabetes group, patients with HbA1c ≥ 7% had lower LES resting pressures and IRP4s compared to HbA1c < 7% patients (p < 0,05). Conclusions: Among patients with symptoms of gastroesophageal reflux symptoms, the proportion of esophageal motility disorder was higher in type 2 diabetes mellitus patients. Compared to the without diabetes group, UES pressure, LES resting pressure, and IPR4s were considerably lower in diabetes group.

Article Details

Keywords

: Gastroesophageal reflux symptoms, type 2 diabetes mellitus, HRM, LES, IRP4s

References

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