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Date Published: 09/09/2023
Abstract Views: 298
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DOI: https://doi.org/10.51298/vmj.v529i2.6462
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Vol. 529 No. 2 (2023)
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Hoàng, Đình Âu, & Trương, T. T. (2023). THE ROLE OF PI-RADS V2.1 CLASSIFICATION ON MAGNETIC RESONANCE IMAGING COMBINED WITH PSA DENSITY IN THE DIAGNOSIS OF PIRADS 3 NODULES ON TRANSITION ZONES. Vietnam Medical Journal, 529(2). https://doi.org/10.51298/vmj.v529i2.6462

THE ROLE OF PI-RADS V2.1 CLASSIFICATION ON MAGNETIC RESONANCE IMAGING COMBINED WITH PSA DENSITY IN THE DIAGNOSIS OF PIRADS 3 NODULES ON TRANSITION ZONES

Đình Âu Hoàng1,, Thị Thanh Trương1
1 Hanoi Medical University Hospital

Main Article Content

Abstract

Purpose: To eValuate the role of PI-RADS V2.1 classification in combination with PSA density (PSA-D) in diagnosing PI-RADS 3 nodules on transition zone nodules, compared with transrectal ultrasound-guided biopsy results. Material and Methods: A retrospectiVe descriptiVe study of 26 male patients with high total PSA and/or urinary disorders. All patients underwent multiparameter prostate magnetic resonance imaging and classified transitional zone nodules according to the PI-RADS V2.1 classification. PI-RADS 3 nodules will be biopsied using transrectal ultrasound guided and then matched with histopathology results and with PSA-D to assess the cancer risk of these PI-RADS 3 nodules on the transition zone PI-RADS when combining PI-RADS V2.1 classification with PSA-D. Results: The mean age of the group of patients in the study was 65.5±9.3, the highest was 83 years old, the lowest was 42 years old. There are 5 patients without urinary disorders, accounting for 19.2%, the rest haVe difficulty urinating or urinary retention. The mean total PSA concentration in the group of patients was 26.3±25.8 ng/ml, the highest was 100 ng/ml, the lowest was 5.3 ng/ml. The mean prostate Volume of the group of patients was 58.5±26.5 cm3, the highest was 137 cm3, the lowest was 21 cm3. The mean PSA-D of the patient group was 0.54±0.54 ng/ml/ cm3, the highest was 1.8 ng/ml/ cm3, the lowest was 0.07 ng/ml/ cm3. There were 17 patients with PSA-D ≥ 0.20 ng/ml/ cm3, 7 patients with PSA-D from 0.10-0.20 ng/ml/cm3, only 2 patients with PSA-D < 0.10 ng/ml/ cm3. Biopsy results of PI-RADS 3 nodules on transition zone showed that only 3 patients had cancer, accounting for 15.4% (01


patient had GS = 6.0; 01 patient had GS = 7 and 01 patient had GS = 7 patients). =9), the rest had no cancer, accounting for 84.6% (including 03 patients


 


with prostatitis, 01 patient with PIN and 19 patients with benign prostatic hypertrophy). All prostate cancer patients had PSA-D > 0.20 ng/ml/cm3, accounting for 17.6%. Conclusion: The combination of PSA-D and PI-RADS V2.1 classification on magnetic resonance imaging played an important role in screening for prostate cancer, excluding unnecessary biopsies. especially for PI-RADS 3 nodules.

Article Details

Keywords

PI-RADS 3 nodules, prostate transition zone cancer, PSA density.

References

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