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Date Published: 09/09/2023
Abstract Views: 226
Views pdf: 143
DOI: https://doi.org/10.51298/vmj.v529i2.6469
Issue
Vol. 529 No. 2 (2023)
Section
Các bài báo
How to Cite
Ngô, T. M. B., Nguyễn, H. N., & Nguyễn, H. H. (2023). STUDYING THE SUB-CHRONIC TOXICITY OF DRY EXTRACT OF YELLOW TEA LEAVES (CAMELLIA HAKODAE NINH). Vietnam Medical Journal, 529(2). https://doi.org/10.51298/vmj.v529i2.6469

STUDYING THE SUB-CHRONIC TOXICITY OF DRY EXTRACT OF YELLOW TEA LEAVES (CAMELLIA HAKODAE NINH)

Thị Mỹ Bình Ngô1,, Hoàng Ngân Nguyễn2, Hồng Hạnh Nguyễn3
1 Thai Nguyen University Of Medicine And Pharmacy
2 Vietnam Military Medical Academy
3 E hospital

Main Article Content

Abstract

The research examines the safety of dry extract of Yellow tea leaVes (Camellia hakodae Ninh). Objectives: Studying the sub-chronic toxicity of dry extract of Yellow tea leaVes Camellia hakodae Ninh (CKL-THV) in rat. Subjects and methods: EValuate sub-chronic toxicity in rats by the guidelines of the Ministry of Health and the OECD. Research results: Continuous oral administration of CKL-THV to rats for 90 days at doses of 0.35 g/kg/24h and 1.05 g/kg/24h didn’t cause statistically significantly changed in body weight, the number of erythrocytes, leukocytes, hemoglobin concentration, AST, ALT, creatinin and total cholesterol. In addition, CKL-THV did’t cause any change in histology of liVer and kidney of experimented rats. Conclusion: CKL-THV was safe in sub-chronic toxicity studies in experimental mices and rats at the study doses.

Article Details

Keywords

The safety, sub-chronic toxicity, Yellow tea, Camellia hakodae

References

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