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Date Published: 09/09/2023
Abstract Views: 212
Views pdf: 147
DOI: https://doi.org/10.51298/vmj.v529i2.6502
Issue
Vol. 529 No. 2 (2023)
Section
Các bài báo
How to Cite
Hà, M. T., & Đỗ, Ánh D. (2023). THE IMPACT OF BODY MASS INDEX ON NT- proBNP VALUES IN HEART FAILURE PATIENTS. Vietnam Medical Journal, 529(2). https://doi.org/10.51298/vmj.v529i2.6502

THE IMPACT OF BODY MASS INDEX ON NT- proBNP VALUES IN HEART FAILURE PATIENTS

Mạnh Tuấn Hà1,, Ánh Dương Đỗ2
1 University of Medicine and Pharmacy at Ho Chi Minh City
2 City University of Medicine and Pharmacy Hospital. Ho Chi Minh

Main Article Content

Abstract

Background: There is a relationship between N- terminal pro B-type natriuretic peptide (NT- proBNP) leVels and body mass index (BMI). The study aimed to explore                the        impact                of         BMI       on         NT-proBNP concentrations and to examine whether other factors independent of or combined with BMI affect NT- proBNP            Values               in          patients             with                  heart                 failure. Methods: A cross-sectional study was conducted in patients with heart failure class II- IV New York Heart Association   (NYHA).                Results:   A   total      of 293 participants were recruited. The mean age was 68.9±13.2 years, males accounted for 46.4% of the total cohort, the mean BMI was 23.1±4.0 kg/m2, and the median NT- proBNP leVel was 3,776 (1,672-8,806) pg/ml. There was an inVerse relationship between BMI and log NT-proBNP (r=-0.29; p<0.001, Spearman correlation). The independent inVerse determinants of NT-proBNP other than BMI were male sex and eGFR, while the Variables directly correlated to NT-proBNP were LVEF ≤40% and NYHA class III-IV heart failure. Each standard deViation increase in BMI (4 kg/m2) was associated with a 7% decrease in NT-proBNP Values in the total cohort. Conclusions: There is an inVerse association between BMI and NT-proBNP leVels. Other Variables independent of or combined with BMI affect NT-proBNP Values, but BMI has a significant impact on the NT-proBNP Values in the diagnosis of heart failure. Keywords: body mass index (BMI); heart failure;

Article Details

Keywords

body mass index (BMI); heart failure; obesity; N-terminal pro B-type natriuretic peptide (NT- proBNP).

References

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