ĐÁNH GIÁ KẾT QUẢ BAN ĐẦU SỬ DỤNG LUCENTIS TIÊM NỘI NHÃN ĐIỀU TRỊ PHÙ HOÀNG ĐIỂM DO THOÁI HÓA HOÀNG ĐIỂM TUỔI GIÀ, VÕNG MẠC ĐÁI THÁO ĐƯỜNG VÀ TẮC TĨNH MẠCH VÕNG MẠC TẠI BỆNH VIỆN HỮU NGHỊ

Abstract

Objectives: To eValuate the initial results of using Lucentis intraocular injection to treat macular edema due to age-related macular degeneration, diabetic retinopathy and retinal Vein occlusion at Huu Nghi hospital. Medthod: An uncontrolled interVention study was conducted on 71 patient eyes at the Department of Ophthalmology, Huu Nghi Hospital from 1/2018 to 31/5/2021. All patients receiVed 3 consecutiVe intraVitreal injections of Lucentis 1 month apart and were followed up monthly for anatomical and functional outcomes. Results: The intraocular injection method had good anatomical results with the mean central retinal thickness decreasing by approximately 69.41 μm (from 362.59 μm to 257.18 μm) during the study period. The group with central retinal Vein occlusion had the best anatomical response with a 118.5 μm reduction in central retinal thickness compared with pretreatment and 100% in the group with a good central retinal thickness reduction >50 μm. The functional outcome was also significantly improVed with an aVerage increase of

16.63 words after treatment, and there were 23% of eyes with good Visual acuity improVement, none of which had decreased Visual acuity. The group with retinal Vein occlusion had the best functional improVement with an aVerage Visual acuity increased by 29.17 words and 83.3% of eyes had good Visual acuity improVement. The old age macular degeneration group had the worst functional response compared to the other groups. The method of intraocular injection is quite safe because it has a low rate of complications and complications. Conclusion: Intraocular Lucentis injection for the treatment of age- related macular degeneration, diabetic retinopathy and retinal Vein occlusion. It is a safe, low-risk and

effectiVe treatment method.