COMPARISON EFFECTS OF CLEANING STOMACH BY EPUMISAN IN PREPARATION OF SUPER GASTROINTESTINAL ENDOSCOPY PATIENTS AT ENDOSCOPIC CENTER – HANOI MEDICAL UNIVERSITY HOSPITAL

Đào Viết Quân, Lê Quang Hưng, Hoàng Cẩm Tú, Đỗ Thị Việt Phương, Trần Đình Thảo, Đào Văn Long

Main Article Content

Abstract

Objectives: To evaluate the effect of foam cleaning of Espumisan (Simethicone) in patients with upper gastrointestinal endoscopy at Hanoi Medical University Hospital. Methods: Outpatients with indications for upper gastrointestinal endoscopy were randomly assigned to 2 groups: the Simethicone (Espumisan) and the control group, from March 2020 to March 2021, by the method of randomized controlled clinical trial. All endoscopy was performed using a gastrointestinal endoscopy on Fujinon, and evaluated the results on a scale of Mc Nally. Results: 1040 patients who met the criteria were included in the study. The percentage of level A (complete bubble cleaniness) in esophagus, stomach body, fundus, antrum, and duodenum of patients using Espumisan are higher than those of control group (p <0.00001).  Conclusion: The preparation of upper gastrointestinal endoscopy with Espumisan reduces the stagnation of foam in the esophagus, stomach and duodenum effectively, helping to observe and diagnose small lesions more clearly and accurately.

Article Details

References

1. Mojsiewicz-Pieńkowska K. Review of Current Pharmaceutical Applications of Polysiloxanes (Silicones), in Handbook of Polymers for Pharmaceutical Technologies: Processing and Applications, Volume 2 (eds V. K. Thakur and M. K. Thakur), John Wiley & Sons, Inc., Hoboken, NJ, USA. 2015.
2. Bueno L, Beaufrand C, Theodorou V, Andro-Delestrain M-C. Influence of simethicone and alverine on stress-induced alterations of colonic permeability and sensitivity in rats: beneficial effect of their association: Alverine, simethicone and vsiceral pain. Journal of Pharmacy and Pharmacology. 2013;65(4):567-73.
3. Kheir AEM. Infantile colic, facts and fiction.Italian Journal of Pediatrics. 2012;38(1):34-.
4. Cohen J, Safdi MA, Deal SE, Baron TH, Chak A, Hoffman B, et al. Quality Indicators for Esophagogastroduodenoscopy. The American Journal of Gastroenterology. 2006;101(4):886-91.
5. Kwan V, Devière J. Endoscopy essentials: preparation, sedation, and surveillance. Endoscopy. 2008;40(01):65-70.
6. Enns R. Capsule endoscopy: in search of the ideal image. The American Journal of Gastroenterology. 2008;103(1):83-5.
7. Banerjee B, Parker J, Waits W, Davis B. Effectiveness of preproceduresimethicone drink in improving visibility during esophagogastroduodenoscopy: A double-blind, randomized study [2]. Journal of clinical gastroenterology. 1992;15(3):264-5.
8. Bertoni G, Gumina C, Conigliaro R, Ricci E, Staffetti J, Mortilla M, et al. Randomized placebo-controlled trial of oral liquid simethicone prior to upper gastrointestinal endoscopy. Endoscopy. 1992;24(04):268-70.