REVIEWING 02 CASES OF PRIMITIVE NEUROECTODERMAL TUMOR (PNET) AT OTORHINOLARYNGOLOGY DEPARTMENT OF CHO RAY HOSPITAL

Hạnh Uyên Trần1,, Thị Ngọc Khánh Đỗ1
1 Cho Ray Hospital

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Abstract

Objective: Reviewing clincal symptoms, radiological images and manangement for 2 patients with PNET tumor of infratemporal fossa at ENT department of Cho Ray Hospital. Methods: 02 case reports of PNET tumor of the infratemporal fossa at ENT department of Cho Ray hospital. Results: Both 2 cases present with painful face swelling. The CT-Scan and MRI show ill-defined tumor locate at infratemporal fossa that invade zygomatic bone, temporal fossa, and the skull base. 01 case was treated with transcervical approach ( Sebileau Carrega), biopsy was performed in 1 case. Immunohistochemistry results of 2 cases are PNET. 01 case is undergoing radiotherapy, 1 case has died due to tumor recurrence. Conclusion: PNET tumor is a malignant tumor, rapid growth and rarely seen at the head and neck.  To date, there are no clinical or radiological modalities that could detect this rare tumor early. However, histopathology, immunohistochemistry are keys to its diagnosis.

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References

1. Batsakis JG, Mackay B, el-Naggar AK. Ewing's sarcoma and peripheral primitive neuroectodermal tumor: an interim report. Ann Otol Rhinol Laryngol 1996; 105: 838-843.
2. Stout AP. A tumor of the ulnar nerve. Proc NY Pathol Soc 1918;12:2-12.
3. Hart MN, Earle KM. Primitive neuroectodermal tumors of the brain in children. Cancer 1973;32:890-7.
4. Iezzoni JC, Mills SE. “Undifferentiated” small round cell tumors of the sinonasal tract: Differential diagnosis update. Am J clin Pathol 2005; 124: 110- 121.
5. Yuwanati M, Tupkari J, Mhaske S, Joshi P (2013) Primitive neuroectodermal tumor of the posterior mandible: A case report. J Clin Exp Invest 4: 101-104.
6. Carvajal R, Meyer P. Ewing’s sarcoma and primitive neuroectodermal family of tumor. Hematol Oncol Clin North Am. June 2005; 19: 501-525.