FACTORS PREDICTING 1-YEAR MORTALITY AFTER TRANSCATHETER AORTIC VALVE IMPLANTATION IN ELDERLY VIETNAMESE PATIENTS WITH SEVERE AORTIC VALVE STENOSIS: INSIGHTS FROM A SINGLE-CENTER EXPERIENCE

Quốc Khoa Nguyễn1,2, Văn Dương Nguyễn3, Thị Thuỳ Lã3, Văn Tân Nguyễn2,3, Đức Công Nguyễn4,, Thành Nhân Võ 2,3
1 Hospital 30-4, Ministry of Public Security
2 University of Medicine and Pharmacy at Ho Chi Minh City
3 Vinmec Central Park International General Hospital, City. oh Chi Minh
4 Pham Ngoc Thach University of Medicine

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Abstract

Objectives: This study aimed to identify the prognostic factors for one-year mortality in elderly Vietnamese patients with symptomatic severe aortic valve stenosis undergoing transcatheter aortic valve implantation (TAVI). Patients and methods: From March 2017 to December 2022, 71 patients (≥60 years old) with symptomatic severe aortic valve stenosis underwent TAVI at Vinmec Central Park Hospital, with a minimum follow-up duration of 1 year. The patient characteristics were analyzed and compared between two groups (survival and mortality) at the one-year mark using VARC-2 criteria. Results: Four patients (5.6%) died within one year after TAVI. The mortality group had a higher prevalence of chronic heart failure, cerebrovascular disease, STS surgical risk score, bicuspid aortic valve, and mean and peak transaortic pressure gradient in the mortality group. Conversely, the survival group had a higher left ventricular ejection fraction (LVEF) and device success rate. Univariate logistic regression analysis identified five factors associated with increased one-year mortality after TAVI, including chronic heart failure, cerebrovascular disease, STS surgical risk score, mean transaortic pressure gradient, and failure of device implantation. Conclusion: The study conducted on 71 elderly Vietnamese patients with severe symptomatic aortic valve stenosis who received TAVI at a single center identified predictive factors for mortality within 1-year, including chronic heart failure, cerebrovascular disease, STS surgical risk score, mean transaortic pressure gradient, and device implantation failure.

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References

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