THE ROLE OF MICRONISED PURIFIED FLAVONOID FRACTION AND SUCRALFATE-CONTAINING OINTMENT IN TREATMENT HEMORRHOIDS

Ngọc Ánh Nguyễn1,, Ngọc Dũng Trần1, Trung Tín Nguyễn2, Văn Hải Nguyễn2, Công Long Nguyễn3, Văn Năng Phạm4, Anh Vũ Phạm5, Quốc Hùng Hà6, Trường Trúc Lâm Nguyễn7, Hữu An Hồ8, Kiên Quyết Trần9, Anh Bắc Hoàng10, Đức Hinh Nguyễn11, Mạnh Cường Lê12, Xuân Hùng Nguyễn13
1 HMU
2 University of Medicine and Pharmacy at Ho Chi Minh City
3 VNU
4 Can Tho University of Medicine - Pharmacy
5 Hue university of medical
6 National Geriatric Hospital
7 Cho Ray Hospital
8 108 Military Central Hospital
9 Saint Paul Hospital Hanoi
10 Thong Nhat Hospital
11 Tam Anh Hospital Hanoi
12 Tue Tinh Hospital
13 Vietnam-Germany Hospital

Main Article Content

Abstract

Background: Hemorrhoids are one of the most common diseases, leading in the group of anorectal diseases in adults. Drug therapy combined with lifestyle modifications plays an important role in the management of hemorrhoids. Objectives and method: A literature review aimed at collecting evidence on the efficacy and role of Micronised purified flavonoid fraction (MPFF) and sucralfate-containing ointment in the treatment of hemorrhoids. and expert opinion interviews (Delphi Method) to assess consensus on recommendations. Results: MPFF can be used as a preferred method of treatment in combination with appropriate dietary and lifestyle changes for patients with grade I and II hemorrhoids. At the same time, MPFF can be an adjuvant treatment for hemorrhoids after surgery/procedure from level II to level IV. Although the evidence on the role of Sucralfate-containing Rectal Ointment is limited in the treatment of hemorrhoids, it is a widely used and proven effective method for local pain relief. Wound healing in patients after hemorrhoidectomy. Conclusion: The consensus of expert opinion recommendations and evidence on the clinical efficacy of MPFF and Sucralfate Rectal Ointment provides a reliable basis for clinicians to choose their method of treatment. Optimal treatment for hemorrhoids.

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References

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