KẾT QUẢ QUẢN LÝ ĐIỀU TRỊ LAO KHÁNG RIFAMPICIN TẠI THÁI NGUYÊN GIAI ĐOẠN 2016-2020 VÀ MỘT SỐ YẾU TỐ LIÊN QUAN

Abstract

Objectives: To describe the results of treatment management of rifampicin-resistant tuberculosis in Thai Nguyen period 2016-2020 and some related factors. Research Method: A cross-sectional descriptive study was conducted on 92 rifampicin-resistant patients in the period 2016-2020 at Thai Nguyen Tuberculosis and Lung Disease Hospital. Results: The mean age of rifampicin-resistant patients was 40.9±12.3, the male proportion was 79.3%. The proportion of TB retreatment was 73.9%, new cases 26.1% and HIV(+) 19.6%. The proportion of lung TB was 97.8%; AFB(+) 72.8%. The proportion of testing adherence during treatment follow-up was 28.3%. The proportion of cure 3.5%, treatment completed 75.5%, death 10.5%, failure 2.3%, dropout 7.0%, transferred out 1.2%. There were relationship between: poor household economic status, TB retreatment, comorbidities, HIV(+), AFB(+), 20 months treatment duration, patients in prison, non-testing adherence and had adverse drug reaction with unsuccessful treatment of rifampicin-resistant (p<0.05). Conclusion: The proportion of RR-TB successful treatment in Thai Nguyen is relatively high, the retreatment and disease characteristics factors are related to unsuccessful treatment.