CĂN NGUYÊN VI KHUẨN GÂY NHIỄM KHUẨN HUYẾT SƠ SINH TẠI BỆNH VIỆN NHI TRUNG ƯƠNG

Abstract

Objectives: This study aimed to determine the bacterial causing neonatal sepsis. Method: A prospective, cross-sectional descriptive study, including 202 neonates who treated at Neonatal Center of National Hospital of Pediatrics from January 1, 2021, to December 31, 2022. These patients were diagnosed with neonatal sepsis (less than 72 hours postpartum) and had positive blood culture results. All patients in the present study were divided into 2 groups: early onset sepsis (less than 72 hours postpartum) and late onset sepsis (over than 72 hours postpartum). Results: The rates of infants with early onset sepsis and late onset sepsis were 15.5% and 84.5% respectively. Streptococcus spp is the most common cause of early onset sepsis. Gram-negative bacteria group is the most common cause of late onset sepsis, in which Klebsiella pneumoniae accounts for the highest rate with 35.6%. Full-term infants have the higher risk of developing Streptococcus spp, Staphylococcus aureus, and Escherichia coli infection. Whereas Klebsiella pneumoniae and Serratia marcescens are more common in preterm newborns. Conclusion: Most of pathogens are the negative bacterial generally, particularly in the late onset sepsis group. Klebsiella pneumoniae and Streptococcus spp remain the most common bacterial pathogens.