STUDYING ON SURVIVAL TIME OF PATIENTS WITH TESTICULAR ESISTANT PROSTATE CANCER AFTER CHEMOTHERAPY ACCORDING TO DOCETAXEL - PREDNISOLONE REGIMEN

Anh Tú Đỗ1,, Thị Lệ Dương2
1 K Hospital
2 HMU

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Abstract

Background: Prostate cancer is the second most common cancer in men. Although initial response rates to ADT are as high as 80 to 90%, virtually all patients eventually progress to testicular resistance at 18-24 months. Purpose: To Analysis of survival time of patients with orchiectomy-resistant prostate cancer treated with Docetaxel-Prednisolone regimen at K Hospital and some influencing factors. Methods: Evaluation of survival time of 38 patients with testicular resistant prostate cancer treated with Docetaxel-Prednisolone regimen. Results: Median PFS of patients with ADT response ≥ 12 months was 6.4 months compared with 6,3 months in the ADT response curve < 12 months, p = 0,598. Median PFS in patients with visceral metastasis was 4,6 months compared with 6,8 months in the group without visceral metastasis, p = 0,029. Conclusion: Median progression-free survival was significantly higher in patients treated with 8 or more cycles of chemotherapy and no visceral metastases.

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References

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