TÁC DỤNG ĐIỀU CHỈNH RỐI LOẠN LIPID MÁU CỦA VIÊN NANG LINH QUẾ TRUẬT CAM – NHỊ TRẦN THANG GIA VỊ TRÊN CHUỘT CỐNG TRẮNG

Abstract

Objective: To evaluate the effect of regulating dyslipidemia of the LQTCT-NTT capsule on exogenous dyslipidemia rats. Methods: Wistar rats were induced dyslipidemia by drinking a mixture of cholesterol oil, 2 hours later were given the experimental drugs, continuously for 28 days. Evaluation of blood lipid indexes, macroscopic and microscopic images of liver. Results: LQTCT-NTT dose of 0.28g/kg/day and 0.56g/kg/day reduced blood lipid indexes including Triglyceride, Total cholesterol, LDL-Cholesterol, VLDL- Cholesterol, and Atherogenic index; increase HDL-Cholesterol; reduce belly fat and liver fat. These effects of LQTCT-NTT were comparable to those of Atorvastatin at a dose of 10 mg/kg/day. Conclusion: LQTCT-NTT capsules have good effect in regulating exogenous dyslipidemia in Wistar rats.