STUDYING ON TOXICITY AND EFECTIVENESS OF SOME TYPICAL POISONOUS MUSHROOMS IN VINH PHUC PROVINCE SEED EXTRACT ON BIOCHEMISTRY OF ANIMAL MODEL

Hoàng Anh Tuấn, Hoàng Đắc Thăng

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Abstract

Case series of poisonous mushrooms and plants often occured in Northern provinces of Vietnam. Results of animal studies showed that LD50 of dried Russula emetica mushroom passed through the gastrointestinal tract was 4.912g/kg BW, fresh Russula emetica mushroom was 42.126 g/kg BW. The activity of ALT, GGT in rabbit poisoned was significantly higher on day 1 after poisoning than before exposure (p <0.001). LD50 of dried and fresh Chlorophyllum molybdites mushroom was 3.658 g/kg and 34.913 g/kg BW, respectively. The activity of ALT in rabbit poisoned was significantly higher on day 1 after poisoning than before exposure (p <0.001). The GGT activity increased with no significance difference in all the point's time of the study.  

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