ĐẶC ĐIỂM LÂM SÀNG VÀ VI SINH Ở BỆNH NHÂN VIÊM NỘI TÂM MẠC NHIỄM KHUẨN DO STAPHYLOCOCCUS AUREUS

Abstract

Objectives: To survey the clinical and microbiological characteristics of patients with S.aureus IE. Subjects and methods:  This was a retrospective, cross-sectional and descriptive study performed on patients with S.aureus IE who were admitted to Cho Ray Hospital from January 2015 to December 2019. Results: In the five years (2015-2019), there were 39 hospitalized patients with S.aureus IE. The mean age of patients was 42.9±18.2 years and 53.9% were male. S.aureus IE occurred in 69.2% of patients with native valves; 10.3% with prosthetic valves; 5.1% with congenital heart disease, and 15.4% with no prior cardiovascular disease. The most common portal of entry is cutaneous (23.1%). The most frequent clinical symptom in S.aureus IE was fever (92.3%) and the mean pre-admission duration of fever was 13.5 days. The rate of methicillin-resistant S.aureus (MRSA) was 64.1% and 100% S.aureus were sensitive to vancomycin, teicoplanin, linezolid, and tigecycline. Conclusions: S.aureus IE has several special clinical characteristics that should be taken into consideration and the high rate of MRSA.