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Date Published: 31/07/2021
Abstract Views: 271
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DOI: https://doi.org/10.51298/vmj.v502i2.679
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Vol. 502 No. 2 (2021)
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Các bài báo
How to Cite
Đức Thuận, N. ., & Thành Chung, Đặng . (2021). POST-TRANSPLANT VIRUS INFECTION STATUS AND IMPLICATIONS FOR NEW-ONSET DIABETES AFTER KIDNEY TRANSPLANTATION. Vietnam Medical Journal, 502(2). https://doi.org/10.51298/vmj.v502i2.679

POST-TRANSPLANT VIRUS INFECTION STATUS AND IMPLICATIONS FOR NEW-ONSET DIABETES AFTER KIDNEY TRANSPLANTATION

Nguyễn Đức Thuận, Đặng Thành Chung

Main Article Content

Abstract

Objectives: Analysis of infection incidence of some viruses and the association with new-onset diabetes after renal transplantation (NODAT) in subjects three months post-transplantation. Subjects and methods: ncluding 508 patients with kidney post-transplant more than three months who are followed up and treated at Viet Duc University Hospital from September 2017 to April 2018. All patients volunteered to participate in the study. Collect blood and urine in the morning before eating and taking immunosuppressants. Using Realtime PCR to detect the presence of hepatitis B virus (HBV), hepatitis C virus (HCV), cytomegalovirus (CMV), and BK polyomavirus ( BK) in the patient's blood; BK virus is also assessed for the presence in the urine. Patients were diagnosed with new-onset diabetes after renal transplantation based on the American Diabetes Association (ADA). Results: n 508 subjects, in blood, there were: 28/436 patients (6.42%) positive for HBV-DNA; 24/444 (5.54%) positive for HCV-RNA; 35/395 (8.86%) patients positive for CMV; 30/493 (6.09%) patients positive for BK; In urine 150/500 (30%) patients positive for BK; 40/508 (7.87%) patients were co-infected with at least two viruses. There is no difference in the rates of NODAT between those infected with the viruses and those who are not infected. Conclusion: The results of this study provide data on infection rates of HBV, HCV, CMV and BK viruses in a large number of subjects and show no association with NODAT in recipients three months after kidney transplantation.

Article Details

Keywords

post-transplant virus infection, new-onset diabetes after renal transplantation

References

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