CLINICAL AND PARA-CLINICAL CHARACTERISTICS AND THE EFFECTIVENESS OF PHOTOTHERAPY IN NEONATES WITH INDIRECT HYPERBILIRUBINEMIA JAUNDICE AT CAN THO

Quang Khải Trần1,, Minh Phương Nguyễn1, Quang Nghĩa Bùi1, Thị Mỹ Liên Nguyễn1, Đức Trí Nguyễn2, Mạnh Cường Nguyễn3
1 Can Tho University of Medicine - Pharmacy
2 Can Tho Children's Hospital
3 Hospital 103, Military Medical Academy

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Abstract

Objectives: To describe the clinical, para-clinical characteristics and evaluate of the effectiveness of phototherapy in neonates with indirect hyperbilirubinemia jaundice at the Neonatal Department, Can Tho Children’s Hospital. Methods: Cross-sectional descriptive study on 121 infants with indirect hyperbilirubinemia jaundice and used phototherapy as the treatment at Can Tho Children’s Hospital from June 2021 to June 2022. Results: Male sex accounted for 50.4%, with a male/female ratio was 1.02, premature infant rate of 17.4%. There were 35.5% of infants with zone 5 jaundice according to Kramer, mainly seen in premature infants. The average indirect bilirubin concentration was 274.4±78.4 µmol/l. Indirect bilirubin was higher in infants born vaginally than those born by surgery, with comorbidities higher than those without comorbidities (p<0.05). Treatment results: 96.7% of neonates were successfully cured, 3.3% failed and had to exchange transfusion. Infants with comorbidities, had jaundice in zone 5, were born vaginally, jaundice appeared before 7 age day, prolonged phototherapy exposure time. Conclusion: Phototherapy in neonates of indirect hyperbilirubinemia with was highly effective; it needs to focus on infants with infection diseases, jaundice appeared soon in order

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