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RELATIONSHIP BETWEEN SERUM AMMONIA LEVEL AND ESOPHAGEAL VARICES IN PATIENTS WITH CIRRHOSI
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Abstract
Objective: To determine serum ammonia concentrations and the relationship with esophageal varices in cirrhotic patients. Subject and method: prospective, cross-sectional descriptive study carried out on 103 patients with cirrhosis in Digestive Department of 103 military hospital. Venous ammonia levels were quantified by kinetic enzymatic method with glutamate dehydrogenase. Results: The mean serum ammonia level was 71.1 ± 24.8µmol/L, the increase more than 60µmol/L accounted for 63.1%. Ammonia levels were significantly positive correlated to the grade of endoscopic esophageal varices (correlation coefficient r = 0.46, p < 0.001). Conclusion: Serum ammonia level increases in patients with cirrhosis and shows the status of portal hypertension.
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Keywords
Ammonia, esophageal varices, cirrhosis.
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