NGHIÊN CỨU MỘT SỐ CHỈ SỐ XÉT NGHIỆM CỦA BỆNH NHÂN ĐA U TUỶ XƯƠNG CHUỖI NHẸ TẠI BỆNH VIỆN BẠCH MAI

Abstract

Background: Light chain multiple myeloma (LCMM) accounts for about 15-20% of patients with multiple myeloma, has a poor prognosis, has a poorer response to treatment than other groups, and is difficult to detect early in hospitals, patients are often diagnosed late with many complications (anemia, kidney failure, osteoporosis). For early and timely diagnosis, studies on the characteristics of common basic tests of patients with LCMM are essential. Objectives: Research of some laboratory indicators of LCMM patients who come for examination and treatment at Bach Mai Hospital. Subjects, research methods: A cross-sectional descriptive study on 50 patients newly diagnosed with LCMM from 01/2018 to 07/2022, treated at Bach Mai Hospital. Results: Patients with LCMM had low rates of hyperproteinemia, hypoalbuminemia, and A/G inversion, 2%, 8%, and 16%, respectively. The proportion of patients with increased beta-2-microglobulin accounted for 82%. The proportion of patients with normal LDH index accounted for 96%. The proportion of patients with normal total calcium index accounted for 82%. Conclusion: The laboratory indicators of LCMM patients showed hyperproteinemia and beta-2-microglobulin, hypoalbuminemia, low A/G ratio reversed, LDH and total calcium were normal.