CLINICAL CHARACTERISTICS AND RISK FACTORS FOR SEVERITY OF COVID-19 IN OVERWEIGHT AND OBESITY PATIENTS
Main Article Content
Abstract
Background: COVID-19 is a global pandemic with high mortality rate. One of the risk factors for severe COVID-19 is overweight, obesity. These conditions affect the inflammatory response to SARS-COV-2, triggering a cytokine storm. In addition, the comorbidities such as hypertension and diabetes are also risk factors for severity and high mortality in COVID-19 patients. Objectives: (1) Describe clinical performances, investigations and severity of overweight and obesity COVID-19 patients in Hospital of Tropical diseases; (2) Identify risk factors for severity in overweight and obesity COVID-19 patients in Hospital of Tropical diseases. Result: A descriptive cross-sectional study. From July 2021 to December 2021, there were 173 eligible patients, 70 (10.4%) overweight cases, 74 (42.8%) grade I obesity, 29 (16.8%) grade II obesity. The most common clinical symptoms: cough – 153/173 (88.4%), dyspnea – 127/172 (73.3%), and fever – 121/172 (69.9%). 26.6% of the patients were leukocytosis, 53.8% of the population were lymphocytopenia (below 1.0 K/mL), 33% of the patients reported to have cytokine storm. The proportion of critical, severe, moderate, and mild disease was 8.1%, 68.8%, 13.9% and 9.2%, respectively. Risk factors for the severity of COVID-19 were grade II obesity (OR = 10,63 (1,34 – 84,05)) and hypertension (OR = 2,16 (1,03 – 4,56)). Conclusions: Obesity was the risk factor for severity of COVID-19.
Article Details
Keywords
COVID-19, overweight, obesity, severity, risk factors, cytokine storm.
References
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