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Date Published: 06/10/2023
Abstract Views: 96
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DOI: https://doi.org/10.51298/vmj.v530i2.6855
Issue
Vol. 530 No. 2 (2023)
Section
Các bài báo
How to Cite
Nguyễn, T. S., Nguyễn, D. B., Đặng, T. T., Nguyễn, X. K., Trần, N. A., & Lê, P. Đại. (2023). STUDY ON THE MORPHOLOGICAL CHARACTERISTICS OF SOME LIMBIC SYSTEM STRUCTURES ON MAGNETIC RESONANCE IMAGING IN ALCOHOLIC PATIENTS. Vietnam Medical Journal, 530(2). https://doi.org/10.51298/vmj.v530i2.6855

STUDY ON THE MORPHOLOGICAL CHARACTERISTICS OF SOME LIMBIC SYSTEM STRUCTURES ON MAGNETIC RESONANCE IMAGING IN ALCOHOLIC PATIENTS

Thị Sinh Nguyễn1,, Duy Bắc Nguyễn1, Tiến Trường Đặng1, Xuân Kiên Nguyễn1, Ngọc Anh Trần1, Phi Đại Lê2
1 Military Medical University
2 Hai Phong University Of Medicine And Pharmacy

Main Article Content

Abstract

Introduction: Chronic alcohol addiction has been shown to not only affect the size and structure of the brain, but also its function. Objective: to evaluate the relationship between alcohol addiction and changes in hippocampus structure on magnetic resonance imaging (MRI). Methods: A cross-sectional descriptive study was conducted from January 2020 to June 2022 at Thai Nguyen National Hospital. The Stepwise AIC method was used to determine the optimal model related to the volume of the hippocampal gray matter. Results: A total of 140 male patients were selected to participate in the study with a ratio of alcohol addicted to non-alcohol addicted being 1:1. The optimal model suggested a statistically significant relationship between alcohol addiction status and the aforementioned volume measurements. In addition, the intracranial volume was found to be positively correlated with hippocampal gray matter volume. However, age was found to have a negative correlation with hippocampal gray matter volume. Conclusion: Our study provides strong evidence of a relationship between alcohol addiction status and lower hippocampal gray matter volume.

Article Details

Keywords

Hippocampus, Magnetic resonance imaging, alcoholism

References

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