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Date Published: 06/10/2023
Abstract Views: 131
Views pdf: 100
DOI: https://doi.org/10.51298/vmj.v530i2.6856
Issue
Vol. 530 No. 2 (2023)
Section
Các bài báo
How to Cite
Dương, T. T. V., Lê, T. V., Trương, Q. B., Đặng, V. T., Lâm, Q. D., Trương, T. P., & Lê, N. M. (2023). RISK FACTORS FOR TREATMENT FAILURE IN PATIENTS WITH METHICILLIN-RESISTANT STAPHYLOCOCCAL NOSOCOMIAL PNEUMONIA. Vietnam Medical Journal, 530(2). https://doi.org/10.51298/vmj.v530i2.6856

RISK FACTORS FOR TREATMENT FAILURE IN PATIENTS WITH METHICILLIN-RESISTANT STAPHYLOCOCCAL NOSOCOMIAL PNEUMONIA

Thị Thanh Vân Dương1,2,, Thượng Vũ Lê1, Quang Bình Trương1, Vũ Thông Đặng3, Quốc Dũng Lâm3, Thiên Phú Trương3, Ngọc Mai Lê3
1 University of Medicine and Pharmacy at Ho Chi Minh City
2 Can Tho University of Medicine and Pharmacy
3 Cho Ray Hospital

Main Article Content

Abstract

Objective: To determine the risk factors leading to treatment failure of nosocomial pneumonia (NP) due to methicillin-resistant Staphylococcus spp.. Methods: We conducted a prospective, cross-sectional descriptive study with 208 patients with NP due to methicillin-resistant Staphylococcus spp. infection who were treated at the Pulmonary department of Cho Ray Hospital from March 2021 to March 2023. Results: We collected 92 patients who definitely diagnosed with methicillin-resistant staphylococcal nosocomial pneumonia. Among them, had 54 (58.7%) successful treatment, 38 (41.3%) unsuccessful treatment. There was a significant difference between the unsuccessful treatment group and the successful treatment group in the following factors: mean age (58.5 ± 18.5 vs 64.1 ± 12.1), severe NP (94.7% vs 74.1%), respiratory failure (94.7% vs 72.2%), sepsis (86.8% vs 33.3%), septic shock (76.3% vs 14.8%), mechanical ventilation (97.4% vs 25.9%), dialysis (50% vs 13%); with p < 0.05. Conclusion: NP due to methicillin-resistant staphylococcus spp. infection is associated with a high rate of treatment failure, and it is crucial to assess risk factors for treatment failure to treat and predict patients proactively.

Article Details

Keywords

Nosocomial pneumonia, methicillin-resistant Staphylococcus spp., unsuccessful treatment, risk factors.

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