1,064-NM PICOSECOND ND:YAG LASER IN TREATING MELASMA

Thái Vân Thanh Lê1,2, Vi Anh Lê1,, Quốc Hưng Tạ1, Minh Châu Lê1
1 Ho Chi Minh City University of Medicine and Pharmacy Hospital
2 University of Medicine and Pharmacy at Ho Chi Minh City

Main Article Content

Abstract

Objective: To assess the clinical efficacy of the 1064nm Nd:Yag picosecond laser in treating melasma. Methods: Descriptive study of a series of cases, longitudinal follow-up on melasma patients assigned to be treated with a 1064nm Nd:Yag picosecond laser at the Department of Dermatology - Skin Aesthetics, University of Medicine and Pharmacy Hospital in Ho Chi Minh City from August 2021 to August 2022. Results: The average age of the patients was 44.9 ± 6.7%; all patients were femal. The majority of patients (61.1%) had neither a family history of hyperpigmentation nor a history of hyperpigmentation during a previous pregnancy. In the study, 55.6% of patients regularly wore masks, and 55.6% wore masks with light colors. In terms of sunscreen use, only 55.6% of patients regularly applied sunscreen. In the group of patients who used sunscreen, 66.67 percent correctly applied the product. Before treatment, the classification of hyperpigmentation severity revealed that 5.6% of cases were mild, 16,7% were moderate, 22,2% were severe, and 55,6% were very severe. Index L, b, as measured by Colorimeter, increased statistically significant with each treatment (p<0.05), whereas index a change was not statistically significant. In addition, the indices of Spots, Brown Spots, and Porphyrins increased statistically significantly with p<0.05 when evaluating the effectiveness of VISIA treatment. The Melasma Area and Severity Index (MASI) decreased significantly with p<0.001 following each treatment. No patient did not experience improvement following the initial treatment. With each treatment, the Melasma Quality of Life (MELASQoL) score decreased, with P<0.001. 50% of participants in the study reported no subjective or objective adverse effects. The subjective side effects noted in the study were stinging (33.3% of participants) and itching (16.4% of participants). The only reported objective adverse effect was erythema (50%). Conclusion: 1064nm Nd:Yag picosecond laser can be a safe and effective method for melasma treatment.

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References

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