RESULTS OF TREATMENT OF PATIENTS WITH ACUTE PANCREATITIS DUE TO INCREASED TRIGLYCERIDES BY INSULIN THERAPY AT PHU THO GENERAL HOSPITAL

Thị Tuyết Nhung Trần1,, Quốc Tuấn Lê1, Thị Thu Hiền Lê2
1 Medical Center of Thanh Ba
2 Thai Nguyen University Of Medicine And Pharmacy

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Abstract

Objective: “Description of the results of treatment of patients with acute pancreatitis due to hypertriglyceridemia by insulin therapy at Phu Tho General Hospital”. Subjects and methods: 54 patients with hypertriglyceridemia-induced acute pancreatitis were treated with insulin therapy at Phu Tho General Hospital from 7/2022 to 6/2023. Results: The age group 40 - 49 years old accounted for the highest percentage of 37%, the mean age was 47.98 ± 10.02. The number of male patients (88.9%) was more than female (11.1%). After 72h, 48h, 24h and 12h of  insulin therapy, triglyceride decreased by 82.6 ± 8.6%; 77.4 ± 11.2%; 63.8 ± 15.9%; 40.4 ± 16.4%  respectively, compared to the baseline. Insulin therapy has caused some side effects: hypoglycaemia has the rate of 16.7%, the rate of hypokalemia is 18.5%. The success rate is 90.7%. The number of severe patients treated with plasma exchange accounted for 9.3%. The mean hospital stay was 6.1 ± 3.0 days. The average number of days to reach the target TG is 2.5 ± 1.4 days. Conclusion: Insulin therapy have been safe and effective acute TGs lowering therapy

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References

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