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POST-IMMUNIZATION ADVERSE EVENTS ASSOCIATED WITH FIRST DOSES OF THE COVID-19 VACCINE: THE CASE OF HEALTHCARE WORKERS AT THONG NHAT HOSPITAL, HO CHI MINH CITY, VIETNAM
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Abstract
Objectives: The purpose of this study was to conduct a survey of adverse events following first-dose COVID-19 vaccination for healthcare workers at Thong Nhat Hospital, Ho Chi Minh City, Vietnam. Methods: A cross-sectional study was conducted in May 2021, and data were collected through face-to-face interviews with the above-mentioned healthcare workers. The average age of the participants was 37.50±7.91, and 63.46% of them were female. Descriptive statistical and chi-square tests were carried out to analyze the frequency and intensity of self-reported adverse events within seven days of first-dose administration and the factors relating to these occurrences. Results: A total of 312 interviews were completed. The two most common complications were local (62.50%) and systematic (44.86%) complications, among which pain/redness/swelling and fever (above 38°C) occurred very frequently (among 61.54% and 39.64% of the respondents, respectively). Most of the participants experiencing these complications gradually recovered within a few days, and no deaths were recorded. Gender appeared to be positively relevant to these post-vaccination complications, with female workers linked to approximately double the coincidence compared with their male counterparts (OR = 2.212, 95% confidence interval: 1.352–3.618). Conclusion: COVID-19 vaccines are generally safe, with severe events rarely occurring. Gender may be significantly relevant to post-vaccination complications.
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Keywords
Adverse events following immunization, AEFI, COVID-19, Ho Chi Minh City, vaccine, healthcare workers.
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