NGHIÊN CỨU TỔNG QUAN ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VIÊM MŨI XOANG DO NẤM DỊ ỨNG

Abstract

Objectives: Synthetic description of clinical and paraclinical characteristics of allergic fungal sinusitis. Subjects and methods: Scoping Review: articles, studies, lectures, textbooks at 3 databases Pubmed, Google Scholar, Sciencedirect met the research criteria. Result: Found 1012 documents. After analysis, 17 articles were included in the study: the study used a retrospective design of 58.8% (10), a prospective study of 41.1% (7) and the sample size of the studies was less than 50. people (100%). The average age of the participants was under 35 years old 64.7%, male/female ratio 1.24:1.Patients had symptoms of runny nose, stuffy nose, polyp 100% (157); smell disorder 38.2% (60), headache 18.4% (29); postnasal drip17.1% (27). On CT scan: 100% polyp (157). Increased density between uniform blurs 57.3% (57.3). Bone erosion 18.4% (29 and intracranial and orbital enlargement 15.9% (25) The rate of fungal examination on fresh examination is 25.4%, fungal culture (+) is 62.5%. Of which: Aspergillus 45.2% (71), Bipolaris 5.7% (9), Alternaria 5.7% (9) other fungi (Rhizomucor, Fusarium sp..) 5.7% (9). Blood eosinophils > 1 G/L is 39.5% and blood igE (whole and specific) > 600 UI/mL is 46.5% Skin test (+) with fungal allergens is found at a rate of 19, 7% Conclusion: Allergic fungal rhinosinusitis with nasal obstruction, rhinorrhea, and smell disturbance CT scan showed polyps, increased density between homogeneous opacities, and bone erosion. The most common pathogens are Aspergillus, followed by Bipolaris and Alternaria, other less common species often have elevated blood eosinophils and igE.