THAY ĐỔI CỦA MỘT SỐ DẤU ẤN SINH HỌC TIM TRÊN BỆNH NHÂN ĐƯỢC TRIỆT ĐỐT RỐI LOẠN NHỊP TIM BẰNG NĂNG LƯỢNG SÓNG CÓ TẦN SỐ RADIO

Abstract

Objectives: This study aims to evaluate the changes in concentration of some cardiac biomarkers (hs-Troponin T, CK, CK-MB, and CRP-hs) following Radiofrequency ablation (RFA) for arrhythmias. Results: Only hs-TnT concentration increased significantly after EPS procedures; however, the mean concentration was still lower than the upper normal limit (UNL). After RFA, 99% of patients had hs-TnT concentration that rose above the UNL, while only 20.2%, 19.2%, and 17.5% of patients had elevated levels of CK, CK-MB, and CRP-hs, respectively. At 3 and 15 hours after the procedures, only hs-TnT and CK-MB concentrations were significantly higher in the RFA group when compared with the EPS group, while the CK and CRP-hs levels were not statistically different. The hs-TnT level following RFA strongly correlated with procedure duration, number of ablations, and total ablation time. Conclusion: hs-TnT was the most sensitive biomarker for myocardial injury after EPS and RFA procedures. Most patients had higher than normal hs-TnT after RF ablation, and this level correlated strongly with procedure duration, number of ablations, and total ablation time.