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Date Published: 27/10/2023
Abstract Views: 179
Views PDF: 128
DOI: https://doi.org/10.51298/vmj.v531i1.6947
Issue
Vol. 531 No. 1 (2023)
Section
Các bài báo
How to Cite
Nguyễn , T. H. ., Công , Q. T. ., Đinh , V. T. ., & Xa, N. T. . (2023). EVALUATING THE PROPHYLACTIC EFFECT OF PALONOSETRON AND DEXAMETHASONE ON NAUSEA AND VOMITING IN CESAREAN SECTION UNDER SPINAL ANESTHESIA. Vietnam Medical Journal, 531(1). https://doi.org/10.51298/vmj.v531i1.6947

EVALUATING THE PROPHYLACTIC EFFECT OF PALONOSETRON AND DEXAMETHASONE ON NAUSEA AND VOMITING IN CESAREAN SECTION UNDER SPINAL ANESTHESIA

Thanh Hải Nguyễn 1,, Quyết Thắng Công 2, Văn Thuần Đinh 1, Ngọc Tú Xa1
1 Hoa Binh general hospital
2 HMU

Main Article Content

Abstract

Objectives: To evaluate the prophylactic effect of palonosetron and dexamethasone on nausea and vomiting in cesarean section under spinal anesthesia. Subjects and methods: using a controlled clinical trial design, pregnant women > 18 years of age with indications for spinal anesthesia for elective cesarean section were recruited at Hoa Binh Provincial General Hospital from January to July, 2023. Group P: 35 patients received 0.075mg of Palonosetron intravenously 5 – 10 minutes before spinal anesthesia. Group D: 35 patients received 8mg of Dexamethasone intravenously 5 – 10 minutes before spinal anethesia. Results: During surgery, the percentage of patients with nausea and vomiting in group D (22.9%) was higher than in group P (14.3%). After surgery, the proportion of patients with nausea -vomiting in group D (31.4%) was higher than the figure in group P (17.1%), the difference was not statistically significant with p>0.05. Only 1 patient in group D needed treatment for nausea and vomiting. There was no difference in adverse events such as hypotension, tremor, headache, arrhythmia, and allergy in both study groups. Conclusion: Palonosetron's prevention of vomiting and nausea proves more effective than dexamethasone for patients with cesarean section under spinal anesthesia.

Article Details

Keywords

Palonosetro, Dexamethasone, cesarean section

References

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