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Date Published: 02/08/2021
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DOI: https://doi.org/10.51298/vmj.v503i1.695
Issue
Vol. 503 No. 1 (2021)
Section
Các bài báo
How to Cite
Đức Thuận, N. ., & Thành Chung, Đặng . (2021). INCIDENCE OF DENGUE VIRUS INFECTION IN PEDIATRIC PATIENTS IN SOME EPIDEMIC OUTBREAKS IN SOUTHERN VIETNAM. Vietnam Medical Journal, 503(1). https://doi.org/10.51298/vmj.v503i1.695

INCIDENCE OF DENGUE VIRUS INFECTION IN PEDIATRIC PATIENTS IN SOME EPIDEMIC OUTBREAKS IN SOUTHERN VIETNAM

Nguyễn Đức Thuận, Đặng Thành Chung

Main Article Content

Abstract

Objectives: To analyze the prevalence of dengue virus infection in pediatric patients in several epidemics in Ho Chi Minh City, Tien Giang, and Dong Nai provinces. Subjects and methods: 344 pediatric patients diagnosed with febrile dengue phase within three days of fever, admitted to the Department of Pediatrics at Children Hospital No.1 in Ho Chi Minh City, Tien Giang General Hospital and Dong Nai Children Hospital from January 2011 to December 2015, Participation in the study was voluntary and agreed to participate in the study by their relatives and family members. Carry out serum collection of the patient, RNA extraction. Using Multiplex RT-PCR reaction to determine dengue virus serotypes. Results: Patients infected with type 1 (DENV-1), type 2 (DENV-2), type 3 (DENV-3) and type 4 (DENV-4) accounted for 34.01%, 19,77%, 5.52% and 40.70% respectively. Conclusion: There are all four dengue virus serotypes in outbreaks during the study period, with Type 4 (DENV-4) has the highest proportion, and the lowest is type 3 (DENV-3).

Article Details

Keywords

dengue virus, serotypes, pediatric

References

1. Rigau-Pérez JG, Vorndam AV, and Clark GG, The dengue and dengue hemorrhagic fever epidemic in Puerto Rico, 1994-2005. American Journal of Tropical Medicine and Hygiene, 2011. 64: p. 67 - 74.
2. Trương Quang Học and cộng sự, Đánh giá các tác động không mong muốn có thể xảy ra khi phóng thả muỗi Aedes aegypti mang Wolbachia nhằm phòng chống Sốt xuất huyết tại Việt Nam. Dự án Ngăn chặn Sốt xuất huyết tại Việt Nam, 2011: p. 5 - 11.
3. WHO, Update on the Dengue situation in the

Western Pacific Region. Dengue Situation Update Number 467, 2015: p. 5 page.
4. Bộ Y tế, Quyết định 3711 QĐ-BYT ngày 19 tháng 9 năm 2014 của Bộ trưởng Bộ y tế về việc ban hành "Hướng dẫn giám sát và phòng, chống bệnh sốt xuất huyết Dengue". 2014.
5. Lanciotti R. S., et al., Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction. J Clin Microbiol, 1992. 30(3): p. 545-51.
6. NIHE, Final Report on evaluation of communicable diseases surveillance system in Vietnam 2008. 2009, National Institute of Hygiene and Epidemiology: Hanoi.
7. Thai K. T., et al., Clinical, epidemiological and virological features of Dengue virus infections in Vietnamese patients presenting to primary care facilities with acute undifferentiated fever. J Infect, 2010. 60(3): p. 229-37.
8. Takamatsu Y., et al., A Dengue virus serotype 4-dominated outbreak in central Vietnam, 2013. J Clin Virol, 2015. 66: p. 24-6.