THE SITUATION OF MULTI-RESISTANT TB AND TREATMENT RESULTS DURING 3 YEARS 2018-2020 IN DONG THAP PROVINCE

Hữu Thành Nguyễn 1, Thị Tâm Phạm 2, Ngọc Dung Trần2,, Thị Phương Lan Đặng 3, Thị Loan Dương 2, Mẫn Ngọc Hà3, Thị Hồng Của Trịnh 2, Thị Hương Trúc Đinh 2
1 Dong Thap lung hopsital
2 Can Tho University of Medicine - Pharmacy
3 Dong Thap lung hospital

Main Article Content

Abstract

Background: Tuberculosis is still a global health problem, one of the 10 leading causes of death worldwide, especially multidrug-resistant tuberculosis. Currently, the drug-resistance of MTB is a dangerous medical problem, with morbidity and mortality rates constantly increasing in the world, in Vietnam and in Dong Thap. Objectives: 1) Determine the rate and characteristics of drug-resistant tuberculosis in new AFB (+) tuberculosis patients in the 3 years 2018-2020 in Dong Thap province, 2) Evaluate the results of multidrug-resistant tuberculosis treatment in the year 2020 in Dong Thap Province. Subjects and methods: A cross-sectional descriptive and analytical study was conducted on all 229 multi-drug-resistant tuberculosis patients enrolled  for treatment from 2018-2020 in Dong Thap. Record the prevalence of drug-resistant TB/new TB AFB (+), the rate of multi-resistant TB/100.00 people in Dong Thap province. Describe the epidemiological characteristics of multi-drug-resistant tuberculosis patients and evaluate the results of multi-drug-resistant tuberculosis treatment in 3 years 2018-2020 in Dong Thap. Results: In 3 years (2018-2020), 229 cases of drug-resistant TB were recovered, the rate of multi-resistant TB/ number of new TB patients AFB (+) was 1.5%, The rate of multi-resistant tuberculosis/patient treated for tuberculosis is 20%. The rate of multi-drug-resistant tuberculosis/number of tuberculosis cases is 2.6%. The epidemiological characteristics of drug-resistant tuberculosis: The ratio of male/female patients is 4.6; Most of patients are in rural areas (73.80%); are farmers (34.06%) and reside in region 3 (39.7%) according to administrative boundaries. Following 229 MDR TB patients for 3 years from 2018 to 2020, the cure rate was 58.95% (135/229), completion of treatment was 13.54% (31). /229), The treatment success rate (including cure and completion rates) was 72.5% (166/229) and 27.5% (63/229) unsuccessful treatment (including failure rate, dropout rate). treatment, death and transfer to another place).

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