EVALUATION ON SURVIVAL TIME AFTER SURGERY AND EOX REGIMEN CHEMOTHERAPY TO TREAT GASTRIC CANCER IN ELDERLY PATIENTS

Lê Thành Trung, Đoàn Hữu Nghị

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Abstract

Objectives: to evaluate the survival time after surgery and EOX regimen chemotherapy to treat gastric cancer in elderly patients. Subjects and methods: Non-controlled clinical interventional study with vertical follow-up, with a combination of prospective and retrospective study was conducted on 57 elderly patients diagnosed with gastric cancer staged IIa – IIIc and undergoing surgical treatment at K Hospital and E hospital from January, 2009 to December, 2019. Results: Overall survival rate of the study groups of 3 years was 85.6%, of 4 years was 59.7%, of 5 years was 46.7%. The mean overall survival time was 49.7 ± 1.8 months. The disease-free survival rate of 3 years was 63.5%, 4 years was 45.8%, 5 years was 35.6%. The mean disease-free survival time was 44.4 ± 2.1 months. Patients with comorbid conditions of cardiovascular disease had a median survival time of 37.45±3.5 months, which was lower than the mean survival time of the group without comorbid conditions of cardiovascular disease (51.8±1, 51.8±1. 8 months). Conclusions: Adjuvant chemotherapy EOX regimen improved survival time in patients with gastric cancer after radical surgeries.

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References

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