RỐI LOẠN NHIỄM SẮC THỂ Ở THAI PHỤ CÓ KẾT QUẢ SÀNG LỌC NGUY CƠ CAO TẠI BỆNH VIỆN PHỤ SẢN TRUNG ƯƠNG

Abstract

Objectives: to determine the prevalence of chromosomal abnormality in double test high-risk result at 12 weeks pregnancy at the National Hospital of Obstetrics and Gynecology between 2019 and 2020. Results: The average age of high-risk pregnant women was 38,45 ± 5,87; of which 70,7% was over 37,5 years old. In this study, the nuchal traslucency was mostly <2.5mm, accounting for 80.9%; meanwhile, nuchal traslucency 2,5-3mm and > 3mm accounted for 9,8% and 9,3% respectively. The rate of fetus with chromosomal abnormalities was 13/225 (5,8%). In these fetuses, Down's syndrome had the highest rate with 13/225 (5,8%). No Edwards' syndrome and Patau's syndrome were detected in our study. Conclusions: High-risk pregnant women had a high prevalence of chromosomal abnormality (5,8%), all cases of chromosomal abnormality were Down's syndrome.