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Date Published: 01/11/2023
Abstract Views: 334
Views PDF: 139
DOI: https://doi.org/10.51298/vmj.v531i1B.7026
Issue
Vol. 531 No. 1B (2023)
Section
Các bài báo
How to Cite
Đỗ , H. C. ., & Đào , V. T. . (2023). TREATMENT RESULTS OF PATIENTS WITH NON-METASTATIC MELANOMA AT VIETNAM NATIONAL CANCER HOSPITAL. Vietnam Medical Journal, 531(1B). https://doi.org/10.51298/vmj.v531i1B.7026

TREATMENT RESULTS OF PATIENTS WITH NON-METASTATIC MELANOMA AT VIETNAM NATIONAL CANCER HOSPITAL

Huyền Chi Đỗ 1,, Văn Tú Đào 2
1 HMU
2 k hospital

Main Article Content

Abstract

Objectives: Study on some clinical and subclinical characteristics of cutaneous melanoma patients with distant metastatic stage (I, II, III) and evaluate the treatment results of the group of patients studied above. Subjects and research methods: A cross-sectional descriptive study on cutaneous melanoma patients with stage I, II, III skin cancer treated at K hospital from January 2018 to December 2021. The Kapan – Meier method is being used to estimate time to treatment failure and overall survival. Results: The average age was 57.29 years old, the youngest patient was 3 years old and the oldest one was 93 years old, the common age range from 40-79 years old accounted for 73.9%. Tumors are often located in the lower limbs (71.0%). Most tumors were hyperpigmented (96.8%), of which mainly dark brown. The dominant form of warts and ulcers is 32.3% and 35.5%, respectively. Tumor thickness > 4mm (T4) accounted for the highest percentage (61.3%), Clark V (29%), multiplying rate >6/mm2 was 35.5%, the rate of lymphoma infiltrating the tumor was 48, 4%. The rate of patients without lymph node metastasis was 51.6%. The proportion of patients with stage I, II, and III was 6.5%, 45.1%, and 48.4%, respectively. The 1, 2, and 3 year disease-free survival rates were 67.7%, 38.7% and 19.4%, respectively. Overall survival at 1, 2, and 3 years was 77.4%, 51.6% and 45.2%, respectively. The 3-year overall survival in stages I-II and III was 73.3% and 18.8% respectively. Conclusion: Cutaneous melanoma is common over 40 years old. Tumor location is most common in the lower limbs. In most cases there is a change in tumor color and morphology. Tumor thickness > 4mm accounts for the highest rate. The rate of patients without lymph node metastasis was 51.6%. The 1, 2, and 3 year disease-free survival rates were 67.7%, 38.7% and 19.4%, respectively. Overall survival at 1, 2, and 3 years was 77.4%, 51.6% and 45.2%, respectively. The 3-year overall survival in stages I-II and III was 73.3% and 18.8% respectively.

Article Details

Keywords

Cutaneous melanoma, clinical features, subclinical features, treatment results

References

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