TÁC NHÂN GÂY BỆNH VIÊM PHỔI NẶNG CẦN HỖ TRỢ OXY Ở TRẺ TỪ 2 THÁNG ĐẾN 5 TUỔI TẠI BỆNH VIỆN NHI ĐỒNG 1

Abstract

Background: Pneumonia is a common disease in children and a leading cause of death, especially severe pneumonia requiring oxygen support. The identification of the causative agent is still challenging in the current situation, especially in developing countries like Vietnam. By modern techniques such as Real-time PCR, identifying pathogenic microorganisms in severe cases of pneumonia requiring oxygen support is extremely important for the purpose of specific recommendations for diagnosis and treatment. Objectives: To investigate causative agent of severe pneumonia requiring oxygen. Materials and methods: A descriptive cross-sectional study is conducted on 78 children with severe pneumonia requiring oxygen support from 2 months to 5 years old at Children's Hospital 1. Results: Real-time PCR results of nasopharyngeal fluid showed the highest viral-bacterial co-infection (66.7%). The two most common bacterial pathogens are S. pneumoniae (55.7%) and H. influenzae non-type b (46.2%). The two most common viral agents are RSV (35.9%) and CMV (33.3%). The co-infection of S. pneumoniae, H. influenzae non-type b and CMV is the highest. Conclusions: Common bacteria in children from 2 months to 5 years old are S. pneumoniae and H. influenzae non-type b. RSV and CMV are common in infants <12 months of age.