CLINICAL, PARACLINICAL CHARACTERISTICS AND EARLY RESULTS OF 257 BREAST CANCER STAGE 0,1,2 PATIENTS WHO UNDERWENT CONSERVATIVE SURGERY AND LOCAL FLAP RECONSTRUCTION AT K HOSPITAL

Anh Dũng Hoàng1,2,, Hồng Quang Lê1, Văn Quảng Lê1,2
1 k hospital
2 HMU

Main Article Content

Abstract

Objective: To describe clinical and paraclinical characteristics, complication rates and resection margin status in early-stage breast cancer patients undergoing conservative surgery and local flap reconstruction. Research subjects and methods: Uncontrolled clinical trial, follow-up on 257 patients with stage 0, I, II breast cancer undergoing conservative surgery from January 2017 to June 2021 at K Hospital. Results: Mean age: 47.6 years old. 64.6% of patients were pre-menopausal, with B and C bra cups accounting for the majority (92.2%). The most common technique was the lateral reconstructive technique (50.97%) for upper-outer quadrant tumors. Average volume of resection specimens: 204.8 cm3. Average tumor size: 2.00 cm. All patients were immediately evaluated for resection by frozen biopsy, the rate of additional resection was 12.8%. There were 7 reoperation cases with a mastectomy rate of 1.17%. The rate of complications was 11.46%, of which there were 9 cases (3.56%) of late complications. Conclusion: Local flap technique for breast cancer conservation surgery has high oncological safety even for large tumors with a low rate of postoperative complications.

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References

1. Veronesi U, Cascinelli N, Mariani L, et al. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med. Oct 17 2002;347(16):1227-32. doi:10.1056/ NEJMoa020989
2. Bertozzi N, Pesce M, Santi PL, Raposio E. Oncoplastic breast surgery: comprehensive review. European review for medical and pharmacological sciences. Jun 2017;21(11):2572-2585.
3. Clough KB, Ihrai T, Oden S, Kaufman G, Massey E, Nos C. Oncoplastic surgery for breast cancer based on tumour location and a quadrant-per-quadrant atlas. The British journal of surgery. Oct 2012;99(10):1389-95. doi:10.1002/bjs.8877
4. Fitoussi AD, Berry MG, Fama F, et al. Oncoplastic breast surgery for cancer: analysis of 540 consecutive cases [outcomes article]. Plast Reconstr Surg. Feb 2010;125(2):454-62. doi:10.1097/PRS.0b013e3181c82d3e
5. Carter SA, Lyons GR, Kuerer HM, et al. Operative and Oncologic Outcomes in 9861 Patients with Operable Breast Cancer: Single-Institution Analysis of Breast Conservation with Oncoplastic Reconstruction. Annals of surgical oncology. Oct 2016;23(10):3190-8. doi:10.1245/ s10434-016-5407-9
6. Clough KB, van la Parra RFD, Thygesen HH, et al. Long-term Results After Oncoplastic Surgery for Breast Cancer: A 10-year Follow-up. Annals of surgery. Jul 2018;268(1):165-171. doi:10.1097/sla.0000000000002255
7. Olson TP, Harter J, Muñoz A, Mahvi DM, Breslin T. Frozen section analysis for intraoperative margin assessment during breast-conserving surgery results in low rates of re-excision and local recurrence. Annals of surgical oncology. Oct 2007;14(10):2953-60. doi:10.1245/s10434-007-9437-1