TÌNH TRẠNG RỐI LOẠN GLUCOSE MÁU Ở PHỤ NỮ MANG THAI CÓ SUY GIÁP TIÊN PHÁT ĐIỀU TRỊ TẠI BỆNH VIỆN NỘI TIẾT TRUNG ƯƠNG

Abstract

Objective: The study aimed to evaluate blood glucose disorders in pregnant women with primary hypothyroidism treated at the National Hospital of Endocrinology in 2020-2023. Methods: A cross-sectional study (combining retrospective and prospective study) was carried out on 215 women with confirmed primary hypothyroidism undergoing treatment and pregnant who examed at the National Hospital of Endocrinology. Results: A study on 215 pregnant women diagnosed with primary hypothyroidism showed that the cause of hypothyroidism due to autoimmune thyroiditis accounted for the highest 54.9%; due to partial thyroidectomy 20.9%, due to total thyroidectomy 20.0%, due to I131 treatment 3.5%, other hypothyroidism 0.9%. The rate of blood glucose disorders in the study subjects was 41.9%. Of these, diabetes mellitus in pregnancy accounts for 6.5% and gestational diabetes accounts for 35.4%. The rate of blood glucose intolerance during pregnancy in the group of hypothyroidism due to total thyroidectomy was the highest, accounting for 55.8%. The value of gestational age, prenatal BMI and TSH index at the first visit are the risk factors leading to glucose disturbances in pregnancy of the study population. Conclusions: The rate of blood glucose disorders in pregnant women with hypothyroidism is quite high (41.9%). The cause of hypothyroidism is autoimmune thyroiditis, accounting for the highest 54.9%. The value of gestational age, prenatal BMI and TSH index at the first visit were the risk factors leading to glucose disturbances in pregnancy in the trial.