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Date Published: 15/11/2023
Abstract Views: 131
Views PDF: 91
DOI: https://doi.org/10.51298/vmj.v531i2.7177
Issue
Vol. 531 No. 2 (2023)
Section
Các bài báo
How to Cite
Đào , T. H. ., & Nguyễn , M. P. . (2023). ENDOMETRIAL THICKNESS CHANGE IN RESPONSE TO PROGESTERONE ADMINISTRATION AND PREGNANCY OUTCOMES IN FROZEN BLASTOCYST TRANSFER CYCLES. Vietnam Medical Journal, 531(2). https://doi.org/10.51298/vmj.v531i2.7177

ENDOMETRIAL THICKNESS CHANGE IN RESPONSE TO PROGESTERONE ADMINISTRATION AND PREGNANCY OUTCOMES IN FROZEN BLASTOCYST TRANSFER CYCLES

Thị Hằng Đào 1,, Minh Phương Nguyễn 1
1 Vietnam Military Medical Academy

Main Article Content

Abstract

Objective: To evaluate the effect of endometrial thickness change in response to progesterone administration on pregnancy outcomes in frozen blastocyst transfer cycles. Subjects and methods: Prospective study includes 120 frozen blastocyst transfer cycles at the Military Institute of clinical Embryology and Histology, using hormone replacement therapy for endometrial preparation. Endometrial thickness (mm) was measured before progesterone administration and before embryo transfer by transvaginal ultrasound. Evaluation of β-hCG (+) rate, clinical pregnancy rate and ongoing pregnancy rate. Results: Cycles with endometrial compaction accounted for the majority with 50.83%. The endometrial thickness before progesterone administration was 9.82 ± 1.48 mm, and the endometrial thickness on the day of embryo transfer was 9.42 ± 1.31 mm, a statistically significant decrease with p = 0.036. The β-hCG positive rate, clinical pregnancy rate and ongoing pregnancy rate were no statistical differences among the groups with changes in endometrial thickness. Conclusion: The endometrial thickness on the day of embryo transfer was significantly decreased compared with the time before progesterone administration. There were no statistically significant differences in pregnancy outcomes among the groups with changes in endometrial thickness after progesterone administration.

Article Details

Keywords

Endometrial thickness change, progesterone, frozen embryo transfer.

References

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