NHẬN XÉT ĐẶC ĐIỂM HỘI CHỨNG DỄ BỊ TỔN THƯƠNG VÀ MỘT SỐ YẾU TỐ LIÊN QUAN Ở NGƯỜI BỆNH GÚT TẠI BỆNH VIỆN BẠCH MAI

Abstract

Objectives: This study aimed to describe clinical characteristics of frailty syndrome (FS) and assess factors associated with FS among gout patients. Methods: This study was conducted with cross-sectional data from 62 gout patients diagnosed by EULAR/ACR 2015 criteria, who were treated in inpatient settings at the Rheumatology Department of Bach Mai Hospital from October 2022 to May 2023. Results: According to CRAF grading, 82,3% of patients had frailty syndrome, with mild, moderate, and severe frail accounting for 35,5%, 30,6%, and 16,1%, respectively. Pain was the most common symptom among 10 major frailty domains in CRAF, affecting 96,8% of patients, followed by physical limitations and fatigue, both at 53,2%. The prevalence of frailty syndrome among patients who were aged ≥40 and those who were aged <40 was 87,7% and 20%, respectively, showing a significant difference (P = 0,005 <0,05) across age groups. All patients with severe chronic gout had frailty syndrome, whereas 61.5% of gout patients with mild severity presented with this syndrome. A significant difference (P = 0,007 <0,05), was found in the prevalence of frailty syndrome among patients with different levels of disease severity. The prevalence of the frailty syndrome in patients increased with the duration of gout: 100% and 81,2% for patients with the duration of 5 to 10 years and >10 years, respectively, indicating a significant difference (P = 0,025 < 0,05) in the prevalence of frailty syndrome across duration groups. Conclusion: The prevalence of the frailty syndrome was relatively high in gout patients and tended to increase with age and disease duration. Moreover, patients with more severe gout had a higher risk of developing frailty syndrome.