YẾU TỐ LIÊN QUAN ĐẾN BẤT THƯỜNG NHIỄM SẮC THỂ ĐỒ Ở NHỮNG THAI PHỤ ĐƯỢC CHỌC HÚT NƯỚC ỐI TẠI BỆNH VIỆN A THÁI NGUYÊN

Abstract

Faced with the reality of malformations in the community, the accessibility to effective prenatal diagnosis methods and high social acceptance. A Thai Nguyen Hospital has deployed amniocentesis technique to test fetal chromosomes to guide doctors to evaluate and give indications to reduce the child's own pain, but it also reduces the burden on the fetus. heavy on both material and spiritual for the family and the whole society. Objective: To analyze some factors related to chromosomal abnormalities in cases of amniocentesis performed at Thai Nguyen A hospital. Research subjects and methods: including 250 pregnant women who performed amniocentesis in 5 years from 2018 to 2022. The research method was cross-sectional descriptive (retrospective study). Results: the study showed that 16.8% of pregnant women had chromosomal abnormalities. Amniocentesis process 100% performed well and did not cause complications and post-amniocentesis treatment with chromosomal testing to terminate pregnancy was 12.0%. The results of the chromosomal map of pregnant women are related to occupational age; history of pregnant women with medical diseases during pregnancy; The ultrasound results showed neurological malformations (statistically significant with p < 0.05). Conclusion: Abnormalities of chromosomes of pregnant women performing amniocentesis at A Thai Nguyen hospital are related to age; profession; history of medical disease; family history; results of ultrasound and maternal screening serology.