NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG TRÊN BỆNH NHÂN VẢY NẾN MỦ TẠI BỆNH VIỆN DA LIỄU THÀNH PHỐ CẦN THƠ NĂM 2021-2023

Abstract

Background: Pustular psoriasis is a rare clinical form of psoriasis. In particular, systemic pustular psoriasis has a high potential to threaten life and death, so early recognition and timely treatment are extremely important. Objectives: describe clinical and para-clinical characteristics of pustular psoriasis patients at Can Tho City Dermatology Hospital in 2021-2023. Materials and Methods: case-series study on 59 pustular psoriasis patients at Can Tho hospital of Dermato-Venereology in 2021-2023. Results: average age of onset was 32.77±16.75 years old. Of which, the group ≤40 years old accounts for the highest proportion of 69.5%, the group >40 years old accounts for 30.5%. Systemic pustular psoriasis is the most common clinical form, accounting for 100% in our study. Accompanying clinical symptoms include fever (55.9%), nail lesions (54.2%), geographic tongue (55.2%), and psoriatic arthritis (13.6%). Para-clinical features in patients with pustular psoriasis include increased white blood cells (accounting for 76.3%), and blood speed hour 1 and hour 2 sedimentation increased (accounted for 100%), CRP increased (accounted for 84.7%), AST increased (accounted for 13.6%), ALT increased (accounted for 28.8%), albumin decreased (accounted for 62.7 %) and calcium decreased (accounting for 69.5%). Conclusions: Pustular psoriasis is a rare clinical form of psoriasis with diverse clinical manifestations, usually early onset at the age of 40 years or younger. Para-clinical features that need attention include leukocytosis, blood glucose, AST, ALT and calcium.