IMPACT OF TRAFFIC-RELATED AIR POLLUTION ON CHILDREN AGED 13-14 YEARS BY AVEOLAR MACROPHAGE CARBON
Main Article Content
Abstract
Objective: To investigate the correlation between alveolar macrophage carbon and exposure factors of traffic air pollution in children aged 13-14 years in Ho Chi Minh City (HCMC). Research design: Descriptive cross-sectional study. Objects and methods: 80 children aged 13-14 in 2 schools of HCMC. Alveolar Macrophages (AMs) were extracted from sputum samples induced with hypertonic saline. Using ImageJ software*, the carbon amount of 50 AMs per subject was quantified. Exposure factors and respiratory symptoms were investigated using ISAAC** questionnaires. Results: Thirty standardized sputum samples were collected, each contained at least 50 AMs per participant. The median carbon amount in macrophages was 0,294 (0,149 – 1,092). Eighty-seven percent of the participants utilized modes of conveyance such as motorcycles, bicycles, or walking. Thirty-six percent of children had wheezing symptoms and 53% had airway diseases. In addition, 90% of participants reported daily use of facemasks, with 70% using either a nylon or paper mask. There was a positive correlation between exposure time of traffic air pollution and AMs (R=0,01, p <0,001). Conclusions: There was a positive correlation between exposure factors and alveolar macrophages.
Article Details
Keywords
Traffic-related air pollution, alveolar macrophage carbon, respiratory health
References
2. Bunn. H. J, Dinsdale. D, Smith. T, Grigg. J. Ultrafine particles in alveolar macrophages from normal children. Thorax 2001;56: 932-4
3. Hong. Le. T. C. H., Dang. T. N., Ware. R., Phung. D, Thai. P. K, P. D. Sly, et al. (2021) "Using the health beliefs model to explore children's attitudes and beliefs on air pollution". Public Health, 196, 4-9.
4. Norrice. Mary. Liu. Handling of Inhaled Particulate Matter by Alveolar Macrophages in Children with Cystic Fibrosis. the Degree of Doctor of Philosophy. Queen Mary University of London; 2019
5. Kulkarni. N, Pierse. N, Rushton. L, Grigg. J (2006) "Carbon in airway macrophages and lung function in children". N Engl J Med, 355 (1), 21-30.).
6. UNEP US Green building council USGBC, UN-Habitat, Greenpeace, Collaborative for high performance (2020) Chất lượng không khí Việt Nam, https://www.iqair.com/vi/vietnam