A STUDY ON SOME FACTORS RELATED TO METABOLIC SYNDROME IN PATIENTS WITH PLAQUE PSORIASIS AT CAN THO HOSPITAL OF DERMATO-VENEREOLOGY IN 2021-2023

Phạm Trúc Linh Lê1, Hoàng Long Đỗ 1, Thị Ngọc Nga Phạm 1,, Thị Thảo Mai Hà1, Trung Kiên Nguyễn 1
1 Can Tho University of Medicine - Pharmacy

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Abstract

Background: Psoriasis is not only an inflammatory skin disease mediated by cellular immunity but is now considered a systemic inflammatory disease characterized by metabolic syndrome. Objectives: To determine the incidence of metabolic syndrome and some related factors in patients with plaque psoriasis. Materials and Methods: Cross-sectional descriptive study on 70 plaque psoriasis patients examined and treated at Can Tho Hospital of Dermato-Venereology from 2021 to 2023. Results: Male predominance is 55.7%. The average age is 46.60±14.77 years old, the average age of onset is 33.40±13.67 years old, the group <40 years old predominates at 67.1%. The average duration of disease is 12.96±10.69 years. A common symptom is itching (accounting for 85.7%). Location of injury: Trunk (77.1%), scalp and limbs (75.7%), nails (62.9%), joints (10.0%), and folds (27.1%). The average level accounts for the highest rate of 41.1%. The prevalence of metabolic syndrome was 47.1%. Some factors related to metabolic syndrome in patients with plaque psoriasis include age of onset, disease duration, and disease severity. Conclusions: Plaque psoriasis patients with metabolic syndrome have a later age of onset, longer disease duration and more severe disease severity than plaque psoriasis patients without metabolic syndrome.

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References

1. Nguyễn Trường Hải (2022), Nồng độ Calprotectin trong phân và các yếu tố liên quan trên bệnh nhân vảy nến, Luận văn thạc sĩ y học, Trường Đại Học Y Dược Thành Phố Hồ Chí Minh.
2. Trần Viết Quốc Liêm (2022), Khảo sát nồng độ IL-31 huyết thanh và các yếu tố liên quan trên bệnh nhân vảy nến, Luận văn Thạc sĩ, Đại học Y Dược Thành phố Hồ Chí Minh
3. Trần Nguyên Ánh Tú (2021), Nghiên cứu sự thay đổi nồng độ hs-CRP, IL-17A và hiệu quả điều trị bệnh vảy nến thông thường bằng Secukinomab, Luận án tiến sĩ y học, Viện nghiên cứu khoa học y dược lâm sàng 108.
4. Aalemi A. K., Bahain M. B., et al. (2021), "Metabolic Syndrome and Psoriasis: A Case–Control Study in Kabul, Afghanistan", Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 14, tr. 1465.
5. Agarwal K., Das S., et al. (2023), "Psoriasis and its association with metabolic syndrome", Indian Journal of Dermatology. 68(3), tr. 274.
6. Armstrong A. W.,Read C. (2020), "Pathophysiology, clinical presentation, and treatment of psoriasis: a review", Jama. 323(19), tr. 1945-1960.
7. Chan W. M. M., Yew Y. W., et al. (2020), "Prevalence of metabolic syndrome in patients with psoriasis: a cross-sectional study in Singapore", Singapore medical journal. 61(4), tr. 194.
8. El-Komy M. H. M., Mashaly H., et al. (2020), "Clinical and epidemiologic features of psoriasis patients in an Egyptian medical center", JAAD international. 1(2), tr. 81-90.
9. Hao Y., Zhu Y.-j., et al. (2021), "Metabolic syndrome and psoriasis: mechanisms and future directions", Frontiers in Immunology. 12, tr. 711060.
10. Langan S. M., Seminara N. M., et al. (2012), "Prevalence of metabolic syndrome in patients with psoriasis: a population-based study in the United Kingdom", Journal of Investigative Dermatology. 132(3), tr. 556-562.
11. Parisi R., Iskandar I. Y., et al. (2020), "National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study", bmj. 369.