ĐẶC ĐIỂM BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TÝP 2 CÓ GIẢM SỨC CĂNG DỌC NHĨ TRÁI TRÊN SIÊU ÂM ĐÁNH DẤU MÔ CƠ TIM

Abstract

Background: Left atrial remodeling is a silent process in diabetic patients. Identifying early asymptomatic left atrial dysfunction helps screen and prevent early progression to diabetic cardiomyopathy. Therefore, assessing left atrial longitudinal strain reduction by speckle tracking echocardiography is a new method to help detect early left atrial dysfunction. Objectives: Assess clinical and subclinical characteristics of type 2 diabetic patients with reduced left atrial longitudinal strain on speckle tracking echocardiography. Methods: Cross-sectional study, surveying type 2 diabetic patients in the Cardiology Department and Endocrinology Department at Cho Ray Hospital from December 2021 to August 2022. Results: From December 2021 to August 2022, 79 patients were selected for the study. Among them, there are 61 patients have LA longitudinal strain reduction (accounting for 77.2%). The mean age of these patients was 65.8 ± 10.8 years and the proportion of males was 44.3%. These patients have older age, more frequent chronic coronary syndrome and dyslipidemia history, more frequent diabetic complications of foot, nephropathy, peripheral artery disease, higher BUN, serum creatinine and NT-proBNP, lower eGFR, more frequent left ventricular hypertrophy, lower LVEF, higher TRVmax and more frequent grade III left vnetricular diastolic dysfunction compared to patients with normal LA longitudinal strain. The abnormal LA longitudinal strain group has more abnormal LA conduit function and contractile function compared to the normal LA longitudinal strain group. Conclusion: Type 2 diabetic patients have a high incidence of asymptomatic left atrial longitudinal reduction. Reduced left atrial longitudinal strain in patients with type 2 diabetes leads to a concomitant decrease in other left atrial functions.